Poona College of Pharmacy thrives in research and related services due to the extraordinary productivity of its students and faculty. A research-oriented culture is encouraged right from the undergraduate level through project assignments as part of the curriculum. The postgraduate projects are based on the current national and global scientific scenario; practice-based professional and social projects and industrial projects. The doctoral projects in thrust areas are funded by various funding agencies or fellowships from the industry.
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Along with filing patents, the college is also responsible for publishing research articles in high Impact Factor journals.

The Department of Pharmaceutics focuses on the research on formulation science and drug delivery with particular emphasis in Molecular Pharmaceutics, Pharmaceutical Engineering, 3D printing, Novel drug delivery systems such as sustained and controlled release formulation and Nanotechnology, Dry powder inhalers (DPIs), nebulizers, etc., to control various pulmonary diseases and other systemic diseases, Solubility and oral bioavailability enhancement using polymer and lipid-based approaches, Site-specific delivery of therapeutic drugs for the treatment of cancer, Application of Quality by Design (QbD) in drug development, Targeted nanoparticles for tumour and brain targeting, Intranasal drug delivery systems for CNS disorders, Nutraceutical and Cosmeceutical research and Pharmacokinetic and Pharmacodynamic (PK/PD) research.

The Department of Pharmacology has its expertise in preclinical screening of cardiovascular, neurodegenerative, respiratory, metabolic and inflammatory diseases. The department has established animal models for respiratory diseases such as cigarette smoke-induced COPD, alpha naphthyl thiourea (ANTU) induced pulmonary hypertension and bleomycin-induced lung fibrosis. The molecular effects of compounds are evaluated using ELISA, gene expression studies and whole-body plethysmography. They also have expertise in pharmacokinetic and lung deposition study in bronco alveolar lavage fluid and lung tissue.

The Department of Pharmaceutical Chemistry focuses on the in-silico design and development of novel anti-tubercular, anticancer and anti-inflammatory agents. Rational and computer-aided design are used for the synthesis of new chemical entities (NCEs) for various target diseases such as tuberculosis and cancer.

The research conducted by the college leads directly to new and important insights and strategies in drug development to facilitate a more scientific approach to drug delivery and product commercialization.

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